IS CHEMOTHERAPY CARCINOGENIC?
نویسندگان
چکیده
منابع مشابه
Cutaneously applied 4-hydroxytamoxifen is not carcinogenic in female rats.
Tamoxifen is widely used to treat oestrogen-dependent carcinoma of the breast. Previous long-term studies have shown that oral administration of tamoxifen induces hepatoproliferative lesions and hepatocellular tumours in rats. 4-hydroxytamoxifen is an active metabolite of tamoxifen undergoing clinical evaluation for the treatment of various non-malignant breast diseases by topical application. ...
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ژورنال
عنوان ژورنال: CA: A Cancer Journal for Clinicians
سال: 1978
ISSN: 0007-9235
DOI: 10.3322/canjclin.28.1.57